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Perspectives

How Life Sciences Supply Chains Must Respond to Fight COVID-19

2020-05-19


As the pandemic has revealed, life sciences companies must significantly improve their ability to sense and respond to change. Longer term, they must rethink their reliance on far-flung global manufacturing and just-in-time inventory.

The COVID-19 pandemic has created a global shortage of life-saving drugs and supplies, just as social distancing has hampered the life sciences supply chain. Meanwhile, the postponement of nonessential procedures has reduced demand for products such as those used for vaccinations and ophthalmology.

These impacts expose weaknesses caused by a reliance on third-party manufacturers and just-in-time (JIT) inventory — without the risk management and resiliency provided by cloud-based visibility and collaboration platforms, and the redundancy provided by a broader base of suppliers.

To best serve their patients, healthcare providers, business partners and shareholders, life sciences companies must rethink their supply networks and JIT practices. They must also improve their ability to quickly sense and respond to sudden changes in supply, demand and inventory levels.

Planning for the new post COVID-19 normal

Based on our discussions with life sciences leaders, we predict four long-term effects from the pandemic on supply chains:

Much manufacturing heads West.

Today, China and India account for almost a third of drug manufacturing facilities registered by the U.S. Food and Drug Administration. That is because life sciences companies have traditionally organized their supply chains with an emphasis on cost reduction rather than risk management.

We expect China and India to continue to implement temporary export controls for essential drugs and equipment, and other governments to pressure life sciences providers to move production closer to home. To reflect this new environment, life sciences companies will reduce risk through multiple complementary measures. They’ll source ingredients and manufacturing from a more diverse range of partners; pre-approve the use of ingredients; increase reliance on supply chain modeling, optimization and simulation software; and deploy risk-tracking and mitigation platforms.

Supply chain visibility becomes an urgent need.

Currently, a lack of end-to-end supply chain visibility leaves manufacturers blind to which products are in shortest supply, those that might run out given various lockdown scenarios, ideal stockpile levels, and country-of-origin information for every ingredient or part that could affect their manufacturing capability.

In the short term, life sciences companies must quickly deploy supply chain visibility platforms (or enhance their existing platforms) and create a rapid response team as part of a multi-geography, multi-function supply chain command center. Longer term, they will need to deploy supply chain “control towers” — central functions that use data to support decision making aided by scenario planning and simulations.

Significant demand variability.

Today, life science companies struggle to meet demand for personal protective gear, COVID-19 test kits and ventilators, while demand is collapsing for new products and those used in elective procedures. News or scientific reports postulating that certain drugs could help fight the pandemic often trigger a surge in orders and empty shelves. Meeting these fast-changing needs requires an improved ability to “sense” supply and demand trends, which calls for leveraging additional data sources ranging from third-party sales and social media to information captured by connected devices. Dynamic planning will become critical, as will the ability to plan based on probabilities of change rather than firm predictions.

Faster regulatory and manufacturing cycles.

Regulators are already fast-tracking the approval of COVID-19 virus and antibody tests and new and off-schedule treatments, as producers of products and drugs scale their ability to quickly develop, test, manufacture and distribute new treatments.

As the pandemic eases, life sciences companies will seek greater speed by adopting advanced manufacturing capabilities such as preconfigured production modules, single-use technologies that are easier to leverage for multiple products, and continuous manufacturing that replaces multiple batch steps. All of these actions will be required not only to fight COVID-19 but for future pandemics as well.

A quick-response roadmap

Urgently, life sciences companies should more quickly and accurately detect changes in demand and balance their manufacturing capacity with inventory to minimize stock-outs and prevent nonessential stock build-ups.

This improved “sense and respond” capability must include real-time awareness of demand variability across markets. It must also provide continually updated projections for internal and external manufacturing site capacities and logistics partners based on evolving regional lock-down status. To prepare for a quick response, life sciences companies should deploy a cross-functional rapid response team with responsibilities such as those shown below:

Strategize for the new normal

Long-term success in the post COVID-19 world will require shifting from an extensive reliance on far-flung manufacturing partners as well as prioritizing risk mitigation over cost reduction.

Cloud-based supply chain platforms can help life sciences companies more closely coordinate with these new, more diverse partners, influence which companies to work with and how, and balance efficiency and cost optimization against new priorities (such as the resilience of supply networks and risk management).

Among the changes we suggest are:

  • Improve collaboration with and visibility into suppliers, including real-time performance and supply chain capacity data to make informed tactical and operational decisions and to better match supply with demand. This requires agile tools that provide near-real-time visibility, as well as enhanced risk modeling and scenario simulation and data-driven decision making.
  • Reassess every link in the supply chain — from demand and inventory to supply, manufacturing and logistics — using a risk and resiliency lens. Understanding the current state of the supply chain is essential to making the best use of assets such as capital investments and manufacturing capacity as conditions change. Revamped supply chain processes should include more risk scenarios, more what-if analyses, and more complete risk responses and business continuity plans.
  • Consider re-segmenting product lines and prioritizing limited raw materials and manufacturing capacity based on metrics such as a product’s role in preventing the further spread of disease, its profitability and regulatory requirements.
  • Make greater use of automation not only for data-driven decision making, but to implement and monitor safety. This may involve using thermal cameras to monitor employees’ body temperatures, ensure social distancing and confirm that work areas are properly sanitized.
  • Increase cloud usage not only for greater scalability and real-time access, but to enable shifts from paper-based to electronic record keeping in order to speed data collection and prevent infection.
  • Increase automation across operations from workplace monitoring and tracking to the provisioning of hardened desktops or laptops. Reengineer network and information security to facilitate remote working.

The scale of disruption caused by the COVID-19 pandemic is forcing life sciences companies to rethink their supply chain strategies and associated business capabilities. After addressing their most urgent needs, they must rapidly pivot to build medium- and longer-term capabilities that will provide the visibility and flexibility they need to meet future pandemic- and non-pandemic-driven business disruptions.

For more information, visit the Life Sciences section of our website or contact us. Visit our COVID-19 response page for additional insights.

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How Life Sciences Supply Chains Must Respond to Fight COVID-19